HydroCision Receives FDA 510(k) Clearance for SpineJet Perc Resector™ for Hydrodiscectomy™ Using the SpineJet Hydrosurgery System™

ANDOVER, Mass., September 25, 2003 – HydroCision, Inc. (www.hydrocision.com) announced today that the United States Food and Drug Administration has granted 510(k) clearance to market its SpineJet Perc Resector for Hydrodiscectomy in minimally invasive spine surgery. The SpineJet Perc Resector is the first non-thermal fluidjet-based surgical instrument specifically designed for minimally invasive percutaneous microdiscectomy. The device will allow spine surgeons to quickly and effectively complete decompression through a miniature cannula without the thermal effects of other powered instruments. The procedure will be performed on an outpatient basis under local anesthesia allowing patients to return home the same day with minimal post-operative pain and recovery time.

“We have made significant strides in 2003 executing our corporate development strategy to provide a vast portfolio of SpineJet devices for spine surgeons, and to improve the results of a wide array of the spine procedures they perform. The SpineJet Hydrodiscectomy device will be our initial entry into the rapidly growing percutaneous microdiscectomy market, and is a great complement to the SpineJet Resector™ and Curette™ devices,” commented Doug Daniels, President and CEO of HydroCision, Inc. “From microdiscectomies to fusions, we believe the SpineJet family of devices will allow spine surgeons to perform spine procedures faster, more effectively, and less invasively than with instruments currently available."

The SpineJet Perc Resector device leverages HydroCision's patented non-thermal Hydrodrive™ fluidjet-based technology to simultaneously collect and remove nucleus tissue from the disc with a single-powered instrument while preserving the surrounding tissue. The minimally invasive procedure can be performed through a needle-sized cannula thereby minimizing patient post-operative pain and recovery time. HydroCision plans to launch several additional versions of both the SpineJet Perc Resector and the recently introduced family of SpineJet Curette devices during the next few months.

About HydroCision

HydroCision is the leading developer, manufacturer and marketer of fluidjet-based surgical tools that are the foundation of a new surgical modality – ‘hydrosurgery’. Hydrosurgery improves patient care by selectively removing tissue, minimizing collateral damage and bleeding, and promoting the healing process. HydroCision believes its proprietary fluidjet technology is the basis of a new surgical modality because of its compelling features and versatility. Incorporated in 1996, the company continues to develop a broad range of fluidjet-based devices leveraging the HydroDrive™ to meet the needs of multiple specialties. Current investors include Zero-Stage Capital, Newbury Ventures, and Oxford Bioscience Partners.

HydroCision is a registered trademark of HydroCision, Inc. SpineJet, SpineJet Resector, SpineJet Perc Resector, SpineJet Curette, Hydrodiscectomy, HydroDrive, and The Leader in Hydrosurgery are trademarks of HydroCision, Inc.